Patiënten

Patientenzorg

Gezond weefsel beter sparen Dat is het voordeel van protonentherapie.

Bekijk
Waarom protonentherapie Algemene informatie Soorten kanker Ervaringen van patiënten Tips en adviezen Second opinion Jongvolwassen en kanker Lopende studies
Locatie en contactgegevens Wat neemt u mee Vervoer en overnachten Compliment of klacht
Vergoeding van uw behandeling Uw dossier
Research

Research

How HollandPTC works to enhance the benefits of proton therapy

 

View
Our principal investigators Organisations & collaborations Research projects
Pre-clinical and clinical facilities Our research database: how to request data Doing proton research or use our facilities
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HollandPTC

HollandPTC

Voor de beste protonentherapie van nu en later

Over HollandPTC
Onze visie: Samen beter, beter samen Ons team HollandPTC software
Vrienden van Cliëntenraad Diversiteit en gelijkheid

SAMEN BETER, BETER SAMEN

Patiënten

Patientenzorg

Gezond weefsel beter sparen Dat is het voordeel van protonentherapie.

Bekijk
Over de behandeling Waarom protonentherapie Algemene informatie Soorten kanker Ervaringen van patiënten Tips en adviezen Second opinion Jongvolwassen en kanker Lopende studies
Uw bezoek aan HollandPTC Locatie en contactgegevens Wat neemt u mee Vervoer en overnachten Compliment of klacht
Praktische informatie Vergoeding van uw behandeling Uw dossier
Research

Research

How HollandPTC works to enhance the benefits of proton therapy

 

View
Research at HollandPTC Our principal investigators Organisations & collaborations Research projects
Facilities Pre-clinical and clinical facilities Our research database: how to request data Doing proton research or use our facilities
Practical information Practical information on Varian projects R&D communication box Contact
HollandPTC

HollandPTC

Voor de beste protonentherapie van nu en later

Over HollandPTC
Over HollandPTC Onze visie: Samen beter, beter samen Ons team HollandPTC software
Vrienden van Cliëntenraad Diversiteit en gelijkheid

New methodology for developing biomarkers of radiation-induced toxicity in brain tumour patients based on advanced mr imaging of the microvasculature and white matter microstructure

Principal Investigator: Dr. Frans Vos (TU Delft)

PhD student: Chieh Hsien Tseng (TU Delft)

Funding: HollandPTC-Varian 2018

Description

The aim is to create new MR imaging and image analysis techniques for the development of novel biomarkers of radiation toxicity to solve several limitations of currently available methods:

  • High resolution combined dynamic contrast enhanced (DCE) and dynamic susceptibility contrast (DSC) MR imaging in a single MRI protocol
  • Integrated analysis of DCE, DSC and High Angular Resolution Diffusion (HARDI) MRI to disentangle the different microvascular changes that are likely invoked by photon and/or proton therapy, and the effects on the white matter microstructure
  • Development of methods to correlate changes in imaging parameters from DCE, DSC and HARDI MRI to cumulative applied dose and the Common Toxicity Criteria.

 In order to achieve the objectives, clinical pilot studies in brain tumour patients will be conduct, with a focus on low-grade gliomas (LGG): (1) undergoing photon radiotherapy and (2) proton therapy.