Principal Investigator dr. Anggraeini Puspitasari Kokko

Research focus

My research centers on Monte Carlo–based radiation transport modeling as a quantitative foundation for experimental and clinical proton therapy research.

As scientist responsible for the research beam line at Holland Proton Therapy Center, I work at the interface of experiment and computation. I integrate Monte Carlo simulation directly into experimental design, beam characterization, and data interpretation, enabling uncertainty-aware and reproducible research workflows.

I am one of the lead developers and architects of GATE 10, a next-generation Monte Carlo simulation platform built on Geant4. Through this work, I contribute to the development of sustainable, extensible, and scientifically rigorous simulation infrastructures that support advanced modeling and large-scale research collaboration.

Other areas of my research concern proton imaging, including proton radiography and proton computed tomography, physics-based statistical modelling of detectors, and image reconstruction. I also explore physics-informed AI approaches, where machine-learning methods are used as acceleration tools within validated simulation frameworks.

Scientific career

Current positions:

• Senior scientist research beam line

Past positions:

• 2019 – 2024 : Post-Doctoral Researcher, Biophysics / Clinical Radiobiology, GSI Helmholtzzentrum für Schwerionenforschung GmbH, Planckstraße 1, 64291 Darmstadt, Germany.
• 2019 – 2024 : Part- Time Lecturer, Gunma University Heavy-ion Medical Center, 3-39-22 Showamachi, Maebashi, Gunma Prefecture, 371-8511 Japan.
• 2020 : Faculty of ESA (European Space Agency) Summer School/ FACULTY OF ESA-FAIR SPACE RADIATION SCHOOL – 2020.
• 2016-2019 :  Assistant Professor at Gunma University Initiative for Advanced Research (GIAR) and the International Open Laboratory (collaboration with Harvard Medical School / MGH Dr. Held Lab), 3-39-22 Showa-machi, Maebashi, Gunma Prefecture, 371-8511, Japan.
• 2011-2012 :  Medical Counselor at SEAMEO RECFON University of Indonesia, faculty of medicine, Jakarta, Indonesia.
• 2007 :  Research Assistant at Functional Food Forum, Turku, Finland.

Education:

• 2010-2014 PhD in Physics,UniversityofHeidelberg (Magna cum laude : Verygood)2004-2010 Diploma in physics (M.Sc.), University of Heidelberg, Germany2007/2008 Physics at University of Torino, Italy

   

Publications

https://scholar.google.com/citations?hl=en&user=vv_B9qoAAAAJ&view_op=list_works